Though the Keller Graduate School of Management's headquarters are in Chicago, the school operates over 85 campuses and centers throughout the country, concentrated in the West Coast, Midwest and Northeast, particularly. The school began as the CBA Institute, merging with DeVry Institute of Technology in 2002, with the mission to make MBA studies as accessible as possible to working adults. The school offers full-time and online MBAs, allowing students from both programs to 'mix and match' classes taught at actual centers or complete course work on the internet. Students can also switch campuses or centers to suit their location.

Though it is a nontraditional school, Keller's approach to the MBA is fairly typical: its curriculum has a prescribed set of core classes, followed by open scheduling to allow for specialization. MBA students can concentrate in 15 areas, ranging from e-commerce management to marketing, to security management, or participate in an MBA/CPA program. Keller also has 13 graduate certificates, including ones in network and communications management and wireless communications, as well as six specialty masters degrees.

The alumni network at Keller is vast, but not especially close-knit. Students have access to the usual slate of career services through the website and attached campus offices. Social life between students is limited, but most do not choose Keller for more than their degree, as the program also tends to attract older, working students with family obligations.