The largest collegiate school of business in the U.S., the Zicklin School of Business runs the only accredited MBA programs in the CUNY system. It administers three MBA programs: a full-time honors MBA, flex-time MBA and accelerated part-time MBA. The full-time honors program follows the conventional cohort structure throughout the program and includes weekly career seminar, while the flex-time program allows students to schedule classes either full- or part-time. The first year of the full-time program is full of core classes, though requirements are sprinkled throughout the second year as well. All MBA students can choose to earn a general MBA or concentrate in any of 14 specialty areas, which include economics, decision sciences and real estate.

In addition to traditional programs, Zicklin runs a number of joint and specialized degrees. Perhaps most notable are its MBA in health care administration, completed in three years through a partnership with Mt. Sinai, and its JD/MBA with both the New York Law School and Brooklyn Law School. Zicklin also awards MS degrees in seven areas, accountancy, marketing, taxation, statistics, business computer information systems, real estate, and quantitative methods and modeling, as well as post,master certificates and a PhD in business administration.