EMD Serono develops a host of drugs used for treatment in the areas of endocrinology, fertility, neurology, and oncology. The US biopharmaceutical company's flagship product, Rebif, is one of the world's leading drugs for relapsing multiple sclerosis (MS), a neurodegenerative disease. Rebif (which is marketed by
in the US) and Gonal-f (a recombinant hormone therapy for female infertility) are among the top sellers for the firm's parent
. Other marketed therapies are designed to help treat growth hormone deficiency, HIV, and short bowel syndrome. In its development portfolio, product candidates include vaccines and immunotherapies that may help a patient's own immune system fight cancer.
EMD Serono is the US biopharmaceutical division of Merck. Its 30-plus pipeline products include those focused on cancer and neurodegenerative diseases including multiple sclerosis and Parkinson's disease.
Besides its headquarters and commercial facility in Rockland, Massachusetts, EMD Serono operates a research and protein production operation northwest of Boson in the town of Billerica. It also has an office dedicated to government affairs in Washington, DC.
EMD Serono has recently restarted a clinical program studying BLP25 liposome vaccine, a therapeutic vaccine for non-small cell lung cancer. The FDA had previously put the program on hold after a multiple myeloma (plasma cell cancer) patient in a clinical trial developed encephalitis (acute brain inflammation). BLP25 is still on hold for clinical trials in advanced breast cancer.
As part of its neurodegenerative drug development efforts, EMD Serono is helping to advance basic and clinical research on MS through several collaboration agreements. With Boston-based
Brigham & Women's Hospital
it is undertaking basic and clinical research work to discover new treatments. With Fast Forward, a not-for-profit organization established by
The National Multiple Sclerosis Society
, EMD Serono is evaluating and offering funding to promising MS projects engaged in early-stage clinical development. And it is providing
The University of Texas M. D. Anderson Cancer Center
insight into potential cancer treatments to help bring new drugs to patients faster.
In 2015, as part of its strategic partnership with Pfizer, EMD Serono began co-promoting XALKORI, a treatment for non-small cell lung cancer developed by Pfizer. The two companies are working together to bring novel oncology drugs to the market. Previously, they developed and commercialized a monoclonal antibody, avelumab, which was designed to promote the creation of immuno-oncology therapies.